The inpatient ward of our health center is meant for simple things. A child with pneumonia who needs IV antibiotics and oxygen for a day; a dehydrated patient with vomiting and diarrhea who needs some IV fluids, a mother who hemorrhaged after delivery and needs to be monitored overnight for further bleeding. What is actually admitted to our hospital, however, is far more varied, more critical, more surgical, and more chronic than was intended.
This week began with a woman admitted with bloody diarrhea. She was nine months pregnant when she got sick. After four days of illness, she delivered a stillborn baby. She arrived at our hospital five days later, unconscious, with profuse diarrhea and a raw rash across her face. IV fluid and IV antibiotics against dysentery and intra-abdominal infections improved her status somewhat throughout the week, but she still has a tender abdomen and some vomiting, with persistent cough and dizziness. She remains deathly pale and too weak to sit up by herself. There is no fever. When we approach her bed, she asks weakly and fearfully, “how am I doing?” I try to laugh and smile to encourage her, but really, I’m stumped. A blood transfusion may help. So would a CT scan of her abdomen and a chest x-ray and blood cultures. But what we have is IV fluid and IV antibiotics, so that’s what she gets.
She was followed by a similar case – a woman who delivered a stillborn baby at home and then developed a high fever. She was semi-conscious and burning with fever when she arrived. Her uterus was tender. The lab is closed because our only lab technician is gone for a training, so we could only guess at the cause of her fever. She received IV antibiotics against typhoid fever and against post-partum endometritis. Within a day, her fever was gone and her abdomen was less tender. Within two days, she was able to go home. A pregnant mother admitted with hemorrhage after a spontaneous abortion in her fourth month also improved quickly and was discharged home (Edwin removed the fetal parts and treated her uterine hemorrhage – I’m not sure his internal medicine training prepared him for everything he would have to do here!).
One bed has been occupied all week by a baby with Vitamin D deficiency and pneumonia who had been coughing for a month prior to admission. His cough is so violent that he vomits after coughing. The first IV antibiotic failed to improve his respiratory distress; changing to a second IV antibiotic and adding an oral medication failed to cure him also. We tried treating intestinal parasites to see if that may help decrease his vomiting. It didn’t. He continued to cough and vomit. Babies with Vitamin D deficiency are notoriously hard to cure – their constricted ribs and weak immune systems predispose to respiratory infections. Today we discharged him with oral medicines and a follow-up in one week, when our lab is open, to do blood tests. If he is still coughing, we will start him on tuberculosis therapy. Regardless, his prognosis is poor.
The bed beside the Vitamin D deficient baby was occupied by another baby with cough and vomiting, but no vitamin deficiency. The first antibiotic also failed for this child, but fortunately, the second antibiotic worked. Or possibly – the pneumonia was never bacterial at all, it was viral, and it happened to improve at the same time that the second antibiotic was started. Regardless, the baby was discharged home improved. Her bed was immediately filled by another child with severe pneumonia, this one semi-conscious with lungs full of crackles. He was dehydrated because he was too lethargic to drink. Within 12 hours of IV antibiotics, he was playful and drinking normally. He also was discharged home.
The bed beside him was occupied by a chubby 2-month old baby who also seemed to have severe pneumonia – a low grade fever plus a respiratory rate of 112 (try breathing 112 times per minute, it’s pretty hard!) with vomiting and diarrhea and constant crying. CONSTANT crying. We eventually had to move the baby to the isolation room because none of the other patients could get any rest. At first the baby did not respond to IV antibiotics, and I was afraid that the fast breathing and fever and diarrhea were actually due to a surgical intra-abdominal problem, but on the second day improved and the baby quieted down. I wanted him to stay longer because he was so little and had been so sick upon presentation, but all the hospital beds were full. He was actually sharing his hospital bed with another patient who was waiting for someone to be discharged. So the baby was sent home early, with a hundred cautions and reasons to return immediately, and early follow-up in the clinic. His bed was immediately filled by another child with severe pneumonia who had been treated as an outpatient but got worse anyway. The new pneumonia patient was older but equally irritable and crying constantly. He also improved with IV medicine, but is still in the hospital because he failed outpatient treatment and early discharge could easily lead to relapse.
The far corner of the isolation room is occupied by a emaciated chronic alcoholic – the town drunk – who lived by himself, and had been bedridden for 2 weeks before presentation. His neighbors finally brought him in when he stopped eating all together. He was comatose and his wasted limbs were rigid. He was hypothermic and his lungs rattled with cough. Of course, a CT scan of his head and liver function tests and blood cultures would have been nice. But of our quick differential diagnosis list – hepatic encephalopathy, stroke, aspiration pneumonia, and alcohol withdrawal – aspiration pneumonia was the only one we could treat. He was started on (you guessed it) IV antibiotics and IV fluid. Amazingly, he did wake up enough to ask for a cigarette, although he is still quite confused. He has developed a fever and remains hypotensive.
A young, healthy appearing man was admitted the same night as the town drunk. He had been treated for typhoid fever and malaria at another clinic, but still had persistent vomiting and weakness. A preliminary HIV test was positive; we recommended confirmatory HIV testing but he refused because it would cause him “too much stress” if he was found to have HIV. After he left, his bed was filled by a young woman who “fell on a knife” and had an infected puncture wound through her forearm. She is deaf and cannot speak, but she smiles a lot, and the infection seems to be improving. An elderly man admitted with “pyomyositis,” a deep infection of the muscle that I’d never heard of before coming to Ethiopia, also seems to be improving. His thigh is still tender but is less swollen. Needle aspiration of the area did not reveal pockets of pus, so he did not require incision of the muscle to drain the infection. He will limp home tomorrow on oral antibiotics.
Also discharged from the hospital this week was an 8-year old boy with swelling of his entire body and heavy protein in his urine – signs of nephrotic syndrome. Usually grounds for a kidney biopsy, but no one was too keen on sticking a needle into his kidney or trying to analyze the glomeruli under the microscope afterwards, so he was treated empirically with high dose steroids and diuretics. He was so puffy that even his scrotum looked like a balloon, but slowly, the edema decreased. He lost more than 14 lbs as the edema disappeared. In a different bed, another 8-year old boy presented with a swollen abdomen and swollen feet. Unlike the first boy, this child had signs of liver failure. We drained liters of yellow ascites fluid out of his distended abdomen, and then referred him for treatment of possible liver or peritoneal tuberculosis.
We also admitted two children with severe dehydration due to vomiting and diarrhea, both of whom improved with injections of anti-vomiting medicine and ORS (oral rehydration solution). The older child was still vomiting when she left, but she had regained consciousness and was urinating plenty – and we needed her bed. The hospital was full. The family stayed in town overnight and will bring the child back today for a checkup.
The hospital is alternately exhausting and fascinating and frustrating. So many people need so much more than we can provide. So few people have the resources to seek care at a higher level, and the referral hospitals themselves often do not have any more resources than we do. So many patients don’t get better. But – so many do. And being limited in resources stretches us mentally, to think of differential diagnoses without the aid of lab tests and to find alternative treatments. We are limited but not helpless. Who knew that IV fluid and IV antibiotics could do so much?